Normal values and red cell indices

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Normal values and red cell indices

1. Mean corpuscular volume (MCV)

                   MCV = PCV in L/L

                      RBC count/L          The normal value is 85±8 fL (77-93 fL)

2. Mean corpuscular hemoglobin (MCH)

       MCH =     Hb/L .

                    RBC count/L

                                               The normal range is 29.5±2.5 pg (27 – 32pg)

3. Mean corpuscular hemoglobin concentration (MCHC)

                   MCHC =   Hb/dL   .

                                 PCV in L/L

The normal value is 32.5±2.5 g/dL (30-35 g/dL)

PCV – packed cell volume or hematocrit is the volume of erythrocytes per liter of whole blood indicating the proportion of plasma and red cells and ranger 40–54% in man and 37–47% in women.

The hemoglobin content in health is 130–167 g/L in men and 115–155 g/L in women.

Mean corpuscular volume (MCV) is the hematocrit divided by the RBC count. It is a measurement of the volume occupied by a single RBC and is an indicator of individual cell size.

Increased values indicate differentials that encompass macrocytic anemia (eg, vitamin B-12 or folate deficiency, liver disease, alcoholism), while decreased values indicate microcytic anemia (eg. iron deficiency anemia, thalassemia, anemia of chronic blood loss). This is the most important of the RBC indices. A normal value can appear when a wide variety of cell sizes are present (ie, macrocyte, microcyte).

Mean corpuscular Hb concentration (MCHC) is the Hb divided by the hematocrit. It represents average concentration of Hb in the red blood cells. The value is expressed as a percentage. Increased values point to spherocytosis (eg, congenital hemolytic anemia), and decreased values indicate iron deficiency, thalassemia, or macrocytic anemia.

Mean corpuscular Hb(MCH) is the Hgb divided by the RBC count. It represents the average weight of Hb in the RBCs and serves to confirm the accuracy of MCV value. Increased values occur in macrocytic anemia, newborns, and infants. Decreased values indicate microcytic anemia.

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